Zhaoxuan Ma


Email

zhaoxuanma@yahoo.com

INTRO

Zhaoxuan Ma is working as a senior principle algorithm engineer at Medtronic plc. His main focus is on medical image analysis and robotic control system. Besides, he develops apps and builds websites.

EXPERTISE

Robot control

Robot arm control system design and related alogrithm development including but not limited to path planning, collision detection and system calibrition.

Deep Learning

Design and implementation of state-of-the-art deep learning architecture on object detection, image classification and semantic segmentation.

IOS App Development

End-to-end life cycle of IOS application development from concept to release and maintenance.

Medical Image Analysis

Immunohistochemistry (IHC) and fluorescent slide scanning. Cell and tissue based quantification like but not limit to immune infiltration, vessel and gland segmentation, lesion detection.

Full Stack Web Development

Develop web application for both front- and back-end including database interaction, authentication, UI design and server-side API development.

SKILLS

ROBOT

KDL, robotics library

PROGRAMMING LANGUAGE

Python, Java, Matlab, Objective-C, C++, C, html, Javascript, css.

DEEP LEARNING

Pytorch, Tensorflow, Keras

WEB

html, Javascript, css, Angular, REST API, AWS, Google Cloud Platform, Firebase.

EXPERIENCE

Jun. 2022 – Present

Medtronic plc

Senior Principle Algorithm Engineer

Shanghai, China

1. Robot guidance system

Development of robot control system and related algorithm including but not limited to robot-workstation communication service, path planning, collision detection and system calibration.

Vertebrae semantic segmentation algorithm development on 3D (CT/3D-carm) and 2D (X-ray) image data.

2. Surgical navigation system

Software and algorithm development of optical surgical navigation system.

Nov. 2018 – Jun. 2022

Tencent

Senior Algorithm Engineer

Shenzhen, China

1. Cervical cancer screening project

Cervical cancer algrithm development based on TBS system, including low-resolution abnormal cell detection; high-resolution multiple class classification; whole slide grading; cell count; slide quality evaluation.

Algorithm (with device partner) has been issued registration certificates for medical devices of class II; instrument along with algorithm deployed has been used in hundreds of medical center; beat or tie with clinical cervical cancer pathologist in "man vs. machine battle".

2. Smart microscope system project

Development of microscope control system in Android app and Wechat mini-program which can control smart microscope remotely and display video streaming.

Other local system function includes: OCR system for screening slide label; video streaming that supports telemedicine; multi-end live annotation and chat system; local and cloud data management system.

Aug. 2012 – Nov. 2018

Cedars-Sinai Medical Center

Research Associate

Los Angeles, US

Development of machine learning tools to complement Gleason grading of prostate cancer.

Development of a deep learning pipeline to quantitate immune infiltrate in inflammatorybowel disease specimens, and colon gland histomorphometry.

Development of a deep learning approach to assess tumor growth patterns inadenocarcinoma of the lung.

Development of a novel 6-antibody staining protocol to quantitate immune infiltrates inhuman cancers.

Imaging and quantification of immunohistochemically stained tissues and cells.

Oct. 2012 – Jan. 2013

Micronuronix

R&D Engineer

Los Angeles, US

Neural signal data processing and analysis software development.

Jun. 2011 – Aug. 2011

GE Healthcare China

Image Quality Engineer

Beijing, China

System level (C-arm) image quality assessment, analysis and improvement on various image algorithms.

EDUCATION

2010 – 2012

University of Southern California

Master of Biomedical Engineering

Los Angeles, US

2006 – 2010

Zhejiang University

Bachelor of Biomedical Engineering

Minor in International Economics and Trade

Zhejiang, China

PUBLICATIONS

  • Semantic Segmentation of Colon Glands in Inflammatory Bowel Disease Biopsies. Z Ma, Z Swiderska-Chadaj, N Ing, H Salemi, D McGovern, B Knudsen, A Gertych. Information Technologies in Biomedicine, Kamień Śląski, Poland, June 2018.

  • Semantic segmentation for prostate cancer grading by convolutional neural networks. N Ing, Z Ma, J Li, H Salemi, C Arnold, B S. Knudsen, A Gertych. Proc. SPIE 10581, Medical Imaging 2018: Digital Pathology, 105811B (6 March 2018).

  • Quantitative analysis of T cell and macrophage immune markers in Her2-positive breast cancer. S L Shiao. A Gertych, Z Ma, X Zhang, C M Burnison, A J Mirhadi, A Jiuliano, B S Knudsen, A Chung, Abstract P3-07-37, Cancer Research 76 (4 Supplement), Cancer Research, February 15, 2016.

  • Novel quantitative imaging algorithms distinguish localized and metastatic high-grade primary prostate cancers. E Miller, A Gertych, Z Ma, N Ing, M Lewis, B Knudsen, I Garraway, The Journal of Urology, Volume 195, Issue 4, e245. Poster presented at the American Urological Association Conference, San Diego, May 2016.

  • Fractal descriptors accurately distinguish between growth patterns of prostate cancers. Z Ma, Y Xiaopu, M Amin, B Knudsen, A Gertych, United States & Canadian Academy of Pathology Annual Meeting, Laboratory Investigation, vol. 95, 399A-399A, 2015. Poster presented at the U.S. and Canadian Academy of Pathology meeting, San Diego, CA, March 2015.

  • Fractal dimensions and lacunarity of nuclear distribution separate benign tissue and cancer grades in radical prostatectomies. C Cheng, Z Ma, S Bhele, S Mohanty, Y-T Chu, D Luthringer, M Amin, B Knudsen, A Gertych., Fractal dimensions and lacunarity of nuclear distribution separate benign tissue and cancer grades in radical prostatectomies. Mod Path 27:396A, 2014. Poster presented at the U.S. and Canadian Academy of Pathology meeting, San Diego, CA, March 2014.

  • A machine learning tool to complement Gleason Grading of Prostate Carcinoma. S Bhele, Z Ma, S Mohanty, S Salman, M B Amin, B Balzer, B S Knudsen, A Gertych. Mod Path 27:217A, 2014. Poster presented at the U.S. and Canadian Academy of Pathology meeting, San Diego, CA, March 2014.

IOS APPS